Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion

FKHR is phosphorylated by protein kinase B (PKB) at Thr24, Ser256 and Ser319 in response to growth factors, stimulating the nuclear exit and inactivation of this transcription factor. Here we identify two further residues, Ser322 and Ser325, that become phosphorylated in insulin-like growth factor-1...

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Pubblicato in:	EMBO J
Autori principali:	Rena, Graham, Woods, Yvonne L., Prescott, Alan R., Peggie, Mark, Unterman, Terry G., Williams, Michayla R., Cohen, Philip
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2002
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125977/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11980723/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.9.2263
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