AKT-Independent Protection of Prostate Cancer Cells from Apoptosis Mediated through Complex Formation between the Androgen Receptor and FKHR

Recent studies suggested that the protection of cell apoptosis by AKT involves phosphorylation and inhibition of FKHR and related FOXO forkhead transcription factors and that androgens provide an AKT-independent cell survival signal in prostate cancer cells. Here, we report receptor-dependent repres...

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Bibliografiske detaljer
Main Authors: Li, Pengfei, Lee, Heehyoung, Guo, Shaodong, Unterman, Terry G., Jenster, Guido, Bai, Wenlong
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC140652/
https://ncbi.nlm.nih.gov/pubmed/12482965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.1.104-118.2003
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