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AKT-Independent Protection of Prostate Cancer Cells from Apoptosis Mediated through Complex Formation between the Androgen Receptor and FKHR

Recent studies suggested that the protection of cell apoptosis by AKT involves phosphorylation and inhibition of FKHR and related FOXO forkhead transcription factors and that androgens provide an AKT-independent cell survival signal in prostate cancer cells. Here, we report receptor-dependent repres...

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Autori principali: Li, Pengfei, Lee, Heehyoung, Guo, Shaodong, Unterman, Terry G., Jenster, Guido, Bai, Wenlong
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC140652/
https://ncbi.nlm.nih.gov/pubmed/12482965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.1.104-118.2003
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