Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion

FKHR is phosphorylated by protein kinase B (PKB) at Thr24, Ser256 and Ser319 in response to growth factors, stimulating the nuclear exit and inactivation of this transcription factor. Here we identify two further residues, Ser322 and Ser325, that become phosphorylated in insulin-like growth factor-1...

Полное описание

Библиографические подробности

Опубликовано в::	EMBO J
Главные авторы:	Rena, Graham, Woods, Yvonne L., Prescott, Alan R., Peggie, Mark, Unterman, Terry G., Williams, Michayla R., Cohen, Philip
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Nature Publishing Group 2002
Предметы:	Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125977/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11980723/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.9.2263
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