Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation
Forkhead transcription factor FKHR (Foxo1) is a key regulator of glucose homeostasis, cell-cycle progression, and apoptosis. It has been shown that FKHR is phosphorylated via insulin or growth factor signaling cascades, resulting in its cytoplasmic retention and the repression of target gene express...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC208749/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/13679577/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1934283100 |
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