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Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation

Forkhead transcription factor FKHR (Foxo1) is a key regulator of glucose homeostasis, cell-cycle progression, and apoptosis. It has been shown that FKHR is phosphorylated via insulin or growth factor signaling cascades, resulting in its cytoplasmic retention and the repression of target gene express...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Matsuzaki, Hitomi, Daitoku, Hiroaki, Hatta, Mitsutoki, Tanaka, Keiji, Fukamizu, Akiyoshi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC208749/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/13679577/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1934283100
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