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Role of the ubiquitin-selective CDC48(UFD1/NPL4) chaperone (segregase) in ERAD of OLE1 and other substrates
The OLE pathway of yeast regulates the abundance of the ER-bound enzyme Δ-9 fatty acid desaturase OLE1, thereby controlling unsaturated fatty acid pools and membrane fluidity. Previously, we showed that this pathway is exquisitely regulated by the ubiquitin/proteasome system. Activation of the pathw...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2002
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125867/ https://ncbi.nlm.nih.gov/pubmed/11847109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.4.615 |
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