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Proteomics of yeast telomerase identified Cdc48-Npl4-Ufd1 and Ufd4 as regulators of Est1 and telomere length

Almost 400 genes affect yeast telomere length, including Est1, which is critical for recruitment and activation of telomerase. Here we use mass spectrometry to identify novel telomerase regulators by their co-purification with the telomerase holoenzyme. In addition to all known subunits, over 100 pr...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Lin, Kah-Wai, McDonald, Karin R., Guise, Amanda J., Chan, Angela, Cristea, Ileana M., Zakian, Virginia A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Pub. Group 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4579843/
https://ncbi.nlm.nih.gov/pubmed/26365526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9290
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