A carregar...
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
Histone deacetylases (HDACs) play important roles in transcriptional regulation and pathogenesis of cancer. Thus, HDAC inhibitors are candidate drugs for differentiation therapy of cancer. Here, we show that the well-tolerated antiepileptic drug valproic acid is a powerful HDAC inhibitor. Valproic a...
Na minha lista:
Main Authors: | , , , , , , , , , , |
---|---|
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2001
|
Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125788/ https://ncbi.nlm.nih.gov/pubmed/11742974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.24.6969 |
Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|