Sumoylation of HDAC2 promotes NF-κB-dependent gene expression

The transcription factor nuclear factor-κB (NF-κB) is crucial for the maintenance of homeostasis. It is incompletely understood how nuclear NF-κB and the crosstalk of NF-κB with other transcription factors are controlled. Here, we demonstrate that the epigenetic regulator histone deacetylase 2 (HDAC...

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Publicado en:Oncotarget
Autores principales: Wagner, Tobias, Kiweler, Nicole, Wolff, Katharina, Knauer, Shirley K., Brandl, André, Hemmerich, Peter, Dannenberg, Jan-Hermen, Heinzel, Thorsten, Schneider, Günter, Krämer, Oliver H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466673/
https://ncbi.nlm.nih.gov/pubmed/25704882
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