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Natural chalcones as dual inhibitors of HDACs and NF-κB
Histone deacetylase enzymes (HDACs) are emerging as a promising biological target for cancer and inflammation. Using a fluorescence assay, we tested the in vitro HDAC inhibitory activity of twenty-one natural chalcones, a widespread group of natural products with well-known anti-inflammatory and ant...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3583578/ https://ncbi.nlm.nih.gov/pubmed/22710558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2012.1870 |
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