Natural chalcones as dual inhibitors of HDACs and NF-κB

Histone deacetylase enzymes (HDACs) are emerging as a promising biological target for cancer and inflammation. Using a fluorescence assay, we tested the in vitro HDAC inhibitory activity of twenty-one natural chalcones, a widespread group of natural products with well-known anti-inflammatory and ant...

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Bibliographic Details
Main Authors: ORLIKOVA, B., SCHNEKENBURGER, M., ZLOH, M., GOLAIS, F., DIEDERICH, M., TASDEMIR, D.
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2012
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583578/
https://ncbi.nlm.nih.gov/pubmed/22710558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2012.1870
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