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Targeting protein inactivation through an oligomerization chain reaction
A general strategy for inactivation of target proteins is presented, which we have termed “oligomerization chain reaction.” This technique is based on the fusion of the self-associating coiled-coil (CC) domain of the nuclear factor promyelocytic leukemia (PML) to target proteins that are able to sel...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The National Academy of Sciences
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122285/ https://ncbi.nlm.nih.gov/pubmed/11842196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042460299 |
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