Targeting protein inactivation through an oligomerization chain reaction

A general strategy for inactivation of target proteins is presented, which we have termed “oligomerization chain reaction.” This technique is based on the fusion of the self-associating coiled-coil (CC) domain of the nuclear factor promyelocytic leukemia (PML) to target proteins that are able to sel...

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Autores principales: Contegno, Francesco, Cioce, Mario, Pelicci, Pier Giuseppe, Minucci, Saverio
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2002
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC122285/
https://ncbi.nlm.nih.gov/pubmed/11842196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042460299
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