Targeting protein inactivation through an oligomerization chain reaction
A general strategy for inactivation of target proteins is presented, which we have termed “oligomerization chain reaction.” This technique is based on the fusion of the self-associating coiled-coil (CC) domain of the nuclear factor promyelocytic leukemia (PML) to target proteins that are able to sel...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2002
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122285/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11842196/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.042460299 |
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