تحميل...

p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis

The activity of the cyclin-dependent kinase inhibitor p27 is controlled by its concentration and subcellular localization. However, the mechanisms that regulate its intracellular transport are poorly understood. Here we show that p27 is phosphorylated on Ser10 in vivo and that mutation of Ser10 to A...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Rodier, Geneviève, Montagnoli, Alessia, Di Marcotullio, Lucia, Coulombe, Philippe, Draetta, Giulio F., Pagano, Michele, Meloche, Sylvain
التنسيق: Artigo
اللغة:Inglês
منشور في: Oxford University Press 2001
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC125773/
https://ncbi.nlm.nih.gov/pubmed/11726503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.23.6672
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