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Glycosylation influences cross-species formation of protease-resistant prion protein

A key event in the transmissible spongiform encephalopathies (TSEs) is the formation of aggregated and protease-resistant prion protein, PrP-res, from a normally soluble, protease-sensitive and glycosylated precursor, PrP-sen. While amino acid sequence similarity between PrP-sen and PrP-res influenc...

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Detalhes bibliográficos
Main Authors: Priola, Suzette A., Lawson, Victoria A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125748/
https://ncbi.nlm.nih.gov/pubmed/11726505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.23.6692
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