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Octapeptide repeat insertions increase the rate of protease-resistant prion protein formation
A central feature of transmissible spongiform encephalopathies (TSE or prion diseases) involves the conversion of a normal, protease-sensitive glycoprotein termed prion protein (PrP-sen) into a pro-tease-resistant form, termed PrP-res. The N terminus of PrP-sen has five copies of a repeating eight a...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2249780/ https://ncbi.nlm.nih.gov/pubmed/16452616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051822606 |
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