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Strains of [PSI(+)] are distinguished by their efficiencies of prion-mediated conformational conversion

Yeast prions are protein-based genetic elements that produce phenotypes through self-perpetuating changes in protein conformation. For the prion [PSI(+)] this protein is Sup35, which is comprised of a prion-determining region (NM) fused to a translational termination region. [PSI(+)] strains (varian...

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Bibliographic Details
Main Authors: Uptain, Susan M., Sawicki, George J., Caughey, Byron, Lindquist, Susan
Format: Artigo
Language:Inglês
Published: Oxford University Press 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC125732/
https://ncbi.nlm.nih.gov/pubmed/11707395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.22.6236
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