Chaperone-supervised conversion of prion protein to its protease-resistant form
Transmissible spongiform encephalopathies (TSEs) are lethal, infectious disorders of the mammalian nervous system. A TSE hallmark is the conversion of the cellular protein PrP(C) to disease-associated PrP(Sc) (named for scrapie, the first known TSE). PrP(C) is protease-sensitive, monomeric, detergen...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC28411/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9391131/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.25.13938 |
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