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Chaperone-supervised conversion of prion protein to its protease-resistant form
Transmissible spongiform encephalopathies (TSEs) are lethal, infectious disorders of the mammalian nervous system. A TSE hallmark is the conversion of the cellular protein PrP(C) to disease-associated PrP(Sc) (named for scrapie, the first known TSE). PrP(C) is protease-sensitive, monomeric, detergen...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences of the USA
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC28411/ https://ncbi.nlm.nih.gov/pubmed/9391131 |
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