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Thrombospondin-2 plays a protective role in multistep carcinogenesis: a novel host anti-tumor defense mechanism

The angiogenic switch during tumorigenesis is thought to be induced by a change in the balance of pro- angiogenic and anti-angiogenic factors. To elucidate the biological role of the endogenous angiogenesis inhibitor thrombospondin-2 (TSP-2) during multistep carcinogenesis, we subjected TSP-2-defici...

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Bibliografiske detaljer
Main Authors: Hawighorst, Thomas, Velasco, Paula, Streit, Michael, Hong, Young-Kwon, Kyriakides, Themis R., Brown, Lawrence F., Bornstein, Paul, Detmar, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC125494/
https://ncbi.nlm.nih.gov/pubmed/11387198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.11.2631
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