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Structural role of countertransport revealed in Ca(2+) pump crystal structure in the absence of Ca(2+)
Ca(2+)-ATPase of sarcoplasmic reticulum is an ATP-powered Ca(2+) pump but also a H(+) pump in the opposite direction with no demonstrated functional role. Here, we report a 2.4-Å-resolution crystal structure of the Ca(2+)-ATPase in the absence of Ca(2+) stabilized by two inhibitors, dibutyldihydroxy...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1253571/ https://ncbi.nlm.nih.gov/pubmed/16150713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506222102 |
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