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Structural role of countertransport revealed in Ca(2+) pump crystal structure in the absence of Ca(2+)

Ca(2+)-ATPase of sarcoplasmic reticulum is an ATP-powered Ca(2+) pump but also a H(+) pump in the opposite direction with no demonstrated functional role. Here, we report a 2.4-Å-resolution crystal structure of the Ca(2+)-ATPase in the absence of Ca(2+) stabilized by two inhibitors, dibutyldihydroxy...

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Sonraí Bibleagrafaíochta
Main Authors: Obara, Koji, Miyashita, Naoyuki, Xu, Cheng, Toyoshima, Itaru, Sugita, Yuji, Inesi, Giuseppe, Toyoshima, Chikashi
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2005
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1253571/
https://ncbi.nlm.nih.gov/pubmed/16150713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506222102
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