A strong signature of balancing selection in the 5′ cis-regulatory region of CCR5

CCR5 encodes a cell surface chemokine receptor molecule that serves as the principal coreceptor, with CD4, for HIV-type 1 (HIV-1). Varied HIV-1 susceptibility and time to progression to AIDS have been associated with polymorphisms in CCR5. Many of these polymorphisms are located in the 5′ cis-regula...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Bamshad, Michael J., Mummidi, Srinivas, Gonzalez, Enrique, Ahuja, Seema S., Dunn, Diane M., Watkins, W. Scott, Wooding, Stephen, Stone, Anne C., Jorde, Lynn B., Weiss, Robert B., Ahuja, Sunil K.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 2002
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124967/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12149450/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.162046399
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