Race-specific HIV-1 disease-modifying effects associated with CCR5 haplotypes

Genetic variation in CC chemokine receptor 5 (CCR5), the major HIV-1 coreceptor, has been shown to influence HIV-1 transmission and disease progression. However, it is generally assumed that the same CCR5 genotype (or haplotype) has similar phenotypic effects in different populations. To test this a...

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Detalhes bibliográficos
Main Authors: Gonzalez, Enrique, Bamshad, Mike, Sato, Naoko, Mummidi, Srinivas, Dhanda, Rahul, Catano, Gabriel, Cabrera, Sonia, McBride, Megan, Cao, Xuan-Hien, Merrill, Gerald, O’Connell, Peter, Bowden, Donald W., Freedman, Barry I., Anderson, Stephanie A., Walter, Elizabeth A., Evans, James S., Stephan, Kevin T., Clark, Robert A., Tyagi, Sanjay, Ahuja, Seema S., Dolan, Matthew J., Ahuja, Sunil K.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18402/
https://ncbi.nlm.nih.gov/pubmed/10518566
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