HIV-1 infection and AIDS dementia are influenced by a mutant MCP-1 allele linked to increased monocyte infiltration of tissues and MCP-1 levels

Studies in humans and in experimental models of HIV-1 infection indicate an important role for monocyte chemoattractant protein-1 (MCP-1; also known as CC chemokine ligand 2), a potent chemoattractant and activator of mononuclear phagocytes (MP) in the pathogenesis of HIV-associated dementia (HAD)....

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Autori principali: Gonzalez, Enrique, Rovin, Brad H., Sen, Luisa, Cooke, Glen, Dhanda, Rahul, Mummidi, Srinivas, Kulkarni, Hemant, Bamshad, Michael J., Telles, Vanessa, Anderson, Stephanie A., Walter, Elizabeth A., Stephan, Kevin T., Deucher, Michael, Mangano, Andrea, Bologna, Rosa, Ahuja, Seema S., Dolan, Matthew J., Ahuja, Sunil K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2002
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC129777/
https://ncbi.nlm.nih.gov/pubmed/12374865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.202357499
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