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Topological determinants of protein folding

The folding of many small proteins is kinetically a two-state process that represents overcoming the major free-energy barrier. A kinetic characteristic of a conformation, its probability to descend to the native state domain in the amount of time that represents a small fraction of total folding ti...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Dokholyan, Nikolay V., Li, Lewyn, Ding, Feng, Shakhnovich, Eugene I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2002
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124342/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12084924/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.122076099
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