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Topological determinants of protein folding

The folding of many small proteins is kinetically a two-state process that represents overcoming the major free-energy barrier. A kinetic characteristic of a conformation, its probability to descend to the native state domain in the amount of time that represents a small fraction of total folding ti...

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Bibliografiske detaljer
Main Authors: Dokholyan, Nikolay V., Li, Lewyn, Ding, Feng, Shakhnovich, Eugene I.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC124342/
https://ncbi.nlm.nih.gov/pubmed/12084924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.122076099
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