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Role of LAMP-2 in Lysosome Biogenesis and Autophagy
In LAMP-2–deficient mice autophagic vacuoles accumulate in many tissues, including liver, pancreas, muscle, and heart. Here we extend the phenotype analysis using cultured hepatocytes. In LAMP-2–deficient hepatocytes the half-life of both early and late autophagic vacuoles was prolonged as evaluated...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Cell Biology
2002
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC124165/ https://ncbi.nlm.nih.gov/pubmed/12221139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-02-0114 |
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