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LAMP proteins are required for fusion of lysosomes with phagosomes

Lysosome-associated membrane proteins 1 and 2 (LAMP-1 and LAMP-2) are delivered to phagosomes during the maturation process. We used cells from LAMP-deficient mice to analyze the role of these proteins in phagosome maturation. Macrophages from LAMP-1- or LAMP-2-deficient mice displayed normal fusion...

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Detalhes bibliográficos
Main Authors: Huynh, Kassidy K, Eskelinen, Eeva-Liisa, Scott, Cameron C, Malevanets, Anatoly, Saftig, Paul, Grinstein, Sergio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783450/
https://ncbi.nlm.nih.gov/pubmed/17245426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601511
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