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ATM-dependent DNA Damage-independent Mitotic Phosphorylation of H2AX in Normally Growing Mammalian Cells

H2AX is a core histone H2A variant that contains an absolutely conserved serine/glutamine (SQ) motif within an extended carboxy-terminal tail. H2AX phosphorylation at the SQ motif (γ-H2AX) has been shown to increase dramatically upon exogenously introduced DNA double-strand breaks (DSBs). In this st...

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Hlavní autoři: McManus, Kirk J., Hendzel, Michael J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1237100/
https://ncbi.nlm.nih.gov/pubmed/16030261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-01-0065
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