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PIP(3) inhibition of RGS protein and its reversal by Ca(2+)/calmodulin mediate voltage-dependent control of the G protein cycle in a cardiac K(+) channel
Regulators of G protein signaling (RGS) accelerate intrinsic GTP hydrolysis on α subunits of trimeric G proteins and play crucial roles in the physiological regulation of G protein-mediated cell signaling. The control mechanisms of the action of RGS proteins per se are poorly clarified, however. We...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC123647/ https://ncbi.nlm.nih.gov/pubmed/11904384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.072073399 |
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