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Interactions of Cations with the Cytoplasmic Pores of Inward Rectifier K(+) Channels in the Closed State

Ion channels gate at membrane-embedded domains by changing their conformation along the ion conduction pathway. Inward rectifier K(+) (Kir) channels possess a unique extramembrane cytoplasmic domain that extends this pathway. However, the relevance and contribution of this domain to ion permeation r...

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Autores principales: Inanobe, Atsushi, Nakagawa, Atsushi, Kurachi, Yoshihisa
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308888/
https://ncbi.nlm.nih.gov/pubmed/21982822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.278531
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