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A regulator of G protein signalling (RGS) protein confers agonist-dependent relaxation gating to a G protein-gated K(+) channel

1. The effects of RGS4 on the voltage-dependent relaxation of G protein-gated K(+) (K(G)) channels were examined by heterologous expression in Xenopus oocytes. 2. While the relaxation kinetics was unaffected by the acetylcholine concentration ([ACh]) in the absence of RGS4, it became dependent on [A...

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Detalhes bibliográficos
Main Authors: Fujita, Satoru, Inanobe, Atsushi, Chachin, Motohiko, Aizawa, Yoshifusa, Kurachi, Yoshihisa
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270023/
https://ncbi.nlm.nih.gov/pubmed/10896722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.00341.x
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