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Conformational flexibility of bacterial RNA polymerase

The structure of Escherichia coli core RNA polymerase (RNAP) was determined by cryo-electron microscopy and image processing of helical crystals to a nominal resolution of 15 Å. Because of the high sequence conservation between the core RNAP subunits, we were able to interpret the E. coli structure...

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Autors principals: Darst, Seth A., Opalka, Natacha, Chacon, Pablo, Polyakov, Andrey, Richter, Catherine, Zhang, Gongyi, Wriggers, Willy
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC123642/
https://ncbi.nlm.nih.gov/pubmed/11904365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052054099
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