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Quantitative prediction of NF-κB DNA– protein interactions

We describe a general method based on principal coordinates analysis to predict the effects of single-nucleotide polymorphisms within regulatory sequences on DNA–protein interactions. We use binding data for the transcription factor NF-κB as a test system. The method incorporates the effects of inte...

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Bibliografiske detaljer
Main Authors: Udalova, Irina A., Mott, Richard, Field, Dawn, Kwiatkowski, Dominic
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC123039/
https://ncbi.nlm.nih.gov/pubmed/12048232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102674699
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