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Quantitative prediction of NF-κB DNA– protein interactions
We describe a general method based on principal coordinates analysis to predict the effects of single-nucleotide polymorphisms within regulatory sequences on DNA–protein interactions. We use binding data for the transcription factor NF-κB as a test system. The method incorporates the effects of inte...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC123039/ https://ncbi.nlm.nih.gov/pubmed/12048232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102674699 |
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