Functional Consequences of a Polymorphism Affecting NF-κB p50-p50 Binding to the TNF Promoter Region

Stimulation of the NF-κB pathway often causes p65-p50 and p50-p50 dimers to be simultaneously present in the cell nucleus. A natural polymorphism at nucleotide −863 in the human TNF promoter (encoding tumor necrosis factor [TNF]) region provides an opportunity to dissect the functional interaction o...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Udalova, Irina A., Richardson, Anna, Denys, Agnes, Smith, Clive, Ackerman, Hans, Foxwell, Brian, Kwiatkowski, Dominic
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102169/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11094063/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.24.9113-9119.2000
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