Quantitative prediction of NF-κB DNA– protein interactions
We describe a general method based on principal coordinates analysis to predict the effects of single-nucleotide polymorphisms within regulatory sequences on DNA–protein interactions. We use binding data for the transcription factor NF-κB as a test system. The method incorporates the effects of inte...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123039/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12048232/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.102674699 |
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