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Conformational pathways in the gating of Escherichia coli mechanosensitive channel

The pathway of the gating conformational transition of Escherichia coli mechanosensitive channel was simulated, using the recently modeled open and closed structures, by targeted molecular dynamics method. The transition can be roughly viewed as a four-stage process. The initial motion under a lower...

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Detalhes bibliográficos
Main Authors: Kong, Yifei, Shen, Yufeng, Warth, Tiffany E., Ma, Jianpeng
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122891/
https://ncbi.nlm.nih.gov/pubmed/11972047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092051099
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