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Conformational pathways in the gating of Escherichia coli mechanosensitive channel
The pathway of the gating conformational transition of Escherichia coli mechanosensitive channel was simulated, using the recently modeled open and closed structures, by targeted molecular dynamics method. The transition can be roughly viewed as a four-stage process. The initial motion under a lower...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The National Academy of Sciences
2002
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122891/ https://ncbi.nlm.nih.gov/pubmed/11972047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092051099 |
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