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Single residue substitutions that change the gating properties of a mechanosensitive channel in Escherichia coli.

MscL is a channel that opens a large pore in the Escherichia coli cytoplasmic membrane in response to mechanical stress. Previously, we highly enriched the MscL protein by using patch clamp as a functional assay and cloned the corresponding gene. The predicted protein contains a largely hydrophobic...

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Bibliografiska uppgifter
Huvudupphovsmän: Blount, P, Sukharev, S I, Schroeder, M J, Nagle, S K, Kung, C
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1996
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC38113/
https://ncbi.nlm.nih.gov/pubmed/8876191
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