Single residue substitutions that change the gating properties of a mechanosensitive channel in Escherichia coli.
MscL is a channel that opens a large pore in the Escherichia coli cytoplasmic membrane in response to mechanical stress. Previously, we highly enriched the MscL protein by using patch clamp as a functional assay and cloned the corresponding gene. The predicted protein contains a largely hydrophobic...
שמור ב:
| הוצא לאור ב: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
1996
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38113/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8876191/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.21.11652 |
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