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Conformational pathways in the gating of Escherichia coli mechanosensitive channel

The pathway of the gating conformational transition of Escherichia coli mechanosensitive channel was simulated, using the recently modeled open and closed structures, by targeted molecular dynamics method. The transition can be roughly viewed as a four-stage process. The initial motion under a lower...

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Hlavní autoři: Kong, Yifei, Shen, Yufeng, Warth, Tiffany E., Ma, Jianpeng
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC122891/
https://ncbi.nlm.nih.gov/pubmed/11972047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092051099
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