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Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA

8-oxoguanine (8-oxoG), ring-opened purines (formamidopyrimidines or Fapys), and other oxidized DNA base lesions generated by reactive oxygen species are often mutagenic and toxic, and have been implicated in the etiology of many diseases, including cancer, and in aging. Repair of these lesions in al...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Hazra, Tapas K., Izumi, Tadahide, Boldogh, Istvan, Imhoff, Barry, Kow, Yoke W., Jaruga, Pawel, Dizdaroglu, Miral, Mitra, Sankar
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122556/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11904416/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.062053799
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