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Mitochondrial targeting of human DNA glycosylases for repair of oxidative DNA damage.

Oxidative damage to mitochondrial DNA has been implicated in human degenerative diseases and aging. Although removal of oxidative lesions from mitochondrial DNA occurs, the responsible DNA repair enzymes are poorly understood. By expressing the epitope-tagged proteins in COS-7 cells, we examined sub...

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Detalhes bibliográficos
Main Authors: Takao, M, Aburatani, H, Kobayashi, K, Yasui, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC147628/
https://ncbi.nlm.nih.gov/pubmed/9611236
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