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Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene.

A distinct nuclear form of human uracil-DNA glycosylase [UNG2, open reading frame (ORF) 313 amino acid residues] from the UNG gene has been identified. UNG2 differs from the previously known form (UNG1, ORF 304 amino acid residues) in the 44 amino acids of the N-terminal sequence, which is not neces...

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Detalhes bibliográficos
Main Authors: Nilsen, H, Otterlei, M, Haug, T, Solum, K, Nagelhus, T A, Skorpen, F, Krokan, H E
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC146498/
https://ncbi.nlm.nih.gov/pubmed/9016624
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