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Deficiency in repair of the mitochondrial genome sensitizes proliferating myoblasts to oxidative damage.

Reactive oxygen species (ROS), generated as a by-product of mitochondrial oxidative phosphorylation, are particularly damaging to the genome of skeletal muscle because of their high oxygen consumption. Proliferating myoblasts play a key role during muscle regeneration by undergoing myogenic differen...

Whakaahuatanga katoa

I tiakina i:
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Ngā kaituhi matua: Bartosz Szczesny, Gabor Olah, Dillon K Walker, Elena Volpi, Blake B Rasmussen, Csaba Szabo, Sankar Mitra
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2013-01-01
Rangatū:PLoS ONE
Urunga tuihono:http://europepmc.org/articles/PMC3774773?pdf=render
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