Experimentally based model of a complex between a snake toxin and the α7 nicotinic receptor

To understand how snake neurotoxins interact with nicotinic acetylcholine receptors, we have elaborated an experimentally based model of the α–cobratoxin–α7 receptor complex. This model was achieved by using (i) a three-dimensional model of the α7 extracellular domain derived from the crystallograph...

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Hlavní autoři: Fruchart-Gaillard, Carole, Gilquin, Bernard, Antil-Delbeke, Stéphanie, Le Novère, Nicolas, Tamiya, Toru, Corringer, Pierre-Jean, Changeux, Jean-Pierre, Ménez, André, Servent, Denis
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2002
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC122499/
https://ncbi.nlm.nih.gov/pubmed/11867717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042699899
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