Experimentally based model of a complex between a snake toxin and the α7 nicotinic receptor

To understand how snake neurotoxins interact with nicotinic acetylcholine receptors, we have elaborated an experimentally based model of the α–cobratoxin–α7 receptor complex. This model was achieved by using (i) a three-dimensional model of the α7 extracellular domain derived from the crystallograph...

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Detalhes bibliográficos
Main Authors: Fruchart-Gaillard, Carole, Gilquin, Bernard, Antil-Delbeke, Stéphanie, Le Novère, Nicolas, Tamiya, Toru, Corringer, Pierre-Jean, Changeux, Jean-Pierre, Ménez, André, Servent, Denis
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122499/
https://ncbi.nlm.nih.gov/pubmed/11867717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042699899
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