Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling

Parkinson's disease (PD) is the most common movement disorder characterized by dopaminergic dysfunction and degeneration. The cause of most PD cases is unknown, although postmortem studies have implicated the involvement of oxidative stress. The identification of familial PD-associated genes of...

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Detalhes bibliográficos
Main Authors: Yang, Yufeng, Gehrke, Stephan, Haque, Md. Emdadul, Imai, Yuzuru, Kosek, Jon, Yang, Lichuan, Beal, M. Flint, Nishimura, Isao, Wakamatsu, Kazumasa, Ito, Shosuke, Takahashi, Ryosuke, Lu, Bingwei
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224636/
https://ncbi.nlm.nih.gov/pubmed/16155123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504610102
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