Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling

Parkinson's disease (PD) is the most common movement disorder characterized by dopaminergic dysfunction and degeneration. The cause of most PD cases is unknown, although postmortem studies have implicated the involvement of oxidative stress. The identification of familial PD-associated genes of...

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Autori principali: Yang, Yufeng, Gehrke, Stephan, Haque, Md. Emdadul, Imai, Yuzuru, Kosek, Jon, Yang, Lichuan, Beal, M. Flint, Nishimura, Isao, Wakamatsu, Kazumasa, Ito, Shosuke, Takahashi, Ryosuke, Lu, Bingwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224636/
https://ncbi.nlm.nih.gov/pubmed/16155123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504610102
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