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Inference of functional regions in proteins by quantification of evolutionary constraints

Likelihood estimates of local rates of evolution within proteins reveal that selective constraints on structure and function are quantitatively stable over billions of years of divergence. The stability of constraints produces an intramolecular clock that gives each protein a characteristic pattern...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Simon, Alexander L., Stone, Eric A., Sidow, Arend
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 2002
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC122447/
https://ncbi.nlm.nih.gov/pubmed/11880638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042692299
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